Today's MLB DFS slate features nine games, kicking off at 6:40 p.m. ET, bringing together compelling matchups including the Cubs vs. Phillies and significant interleague contests. A wealth of pitching talent will grace the mound, notably Chris Sale, who has shown tremendous form lately with a 2.93 ERA and 72 strikeouts in his last 54.2 innings. Joining him are Matthew Boyd, who continues to excel for the Cubs, and rookie Eury Perez, making his highly anticipated return after Tommy John surgery against the struggling Pirates.

As for hitters, Jose Ramirez stands out, especially when facing left-handed pitchers like Wade Miley, demonstrating a .417 average against them this season. Yandy Diaz's powerful history against Boston's Brayan Bello cannot be overlooked, and both Jarren Duran and Shohei Ohtani are in line for potential big performances against respective right-handers.

The Chicago Cubs take on the Washington Nationals tonight, following a strong 8-3 victory in the first game of the series, marking their third consecutive win and seven out of their last eight games.

Matthew Boyd is set to pitch for the Cubs, boasting a solid record of 5-2 with a 3.08 ERA, while MacKenzie Gore takes the mound for the Nationals with a 2-5 record and a 3.16 ERA. The Cubs have thrived with Boyd on the mound, winning five of his last six starts. The Nationals, however, have struggled, winning only five out of 12 starts with Gore this season.

Recent trends suggest the Cubs are performing well on the road, winning five of their last six games away from home. Despite this, the over has been a common outcome in Cubs games, hitting at a 34-21-5 rate this season. Betting odds favor the Cubs at -136 on the moneyline, while the Nationals sit at +115. The total runs for the game is set at 8.0, with betting recommendations leaning towards the over and a spread play on the Nationals at +1.5.

On May 23, 2025, the Chicago Cubs (30-20) face off against the Cincinnati Reds (25-26) at Great American Ball Park. Cubs' Matthew Boyd, boasting a 2.98 ERA, aims to continue the team's winning streak, having won five of their last six games. Meanwhile, Hunter Greene, with an impressive 2.37 ERA, takes the mound for the Reds, who are looking to break a two-game losing streak after winning five straight.

The matchup comes with tight odds. The Cubs are slight favorites at -115 on the moneyline, while the Reds are at -104. The total runs are set at 8.0, indicating a potentially high-scoring game. Boyd’s recent performance includes a solid outing where he allowed three earned runs across six innings. Greene's last start saw him shut out opponents for three innings. Betting trends suggest the Cubs have excelled against teams with losing records, while the Under often hits when Greene is pitching.

At Wrigley Field, five pediatric patients from Advocate Children’s Hospital stole the show as they participated in a unique event with Chicago Cubs players. The children, aged 7 to 15, were thrilled to autograph custom Topps baseball cards featuring their own images. For Liam McGarrity, a 12-year-old dealing with asthma, the experience felt surreal, picturing his future self on a baseball card.

The event also included memorable moments with players like Matthew Boyd, Kyle Tucker, and Justin Turner, who each interacted warmly with the kids. Nico Hoerner, instrumental in organizing the event, aimed to create lasting memories for the patients, emphasizing the importance of sports in bringing families together during challenging times.

The Chicago Cubs have been sending mixed signals in their offseason strategies, transitioning from bold moves to a more conservative approach. After firing David Ross and hiring Craig Counsell, the Cubs made some notable signings but failed to make significant roster additions.

This winter, they traded for Kyle Tucker from the Houston Astros but also let go of Cody Bellinger to the New York Yankees, raising eyebrows among fans. The Cubs' front office is focused on incremental improvements and balancing short-term success with future potential, as they aim to break a playoff drought that has lasted since 2018.